Phentermine has been used for short-term weight management (typically 12 weeks or less) since 1959, while GLP-1 agonists like Ozempic and Mounjaro gained obesity indication approval only in 2021 and 2023 respectively, backed by multi-year trial data
The differences lie in manufacturing oversight (Ozempic is FDA-approved, Strive is compounded), delivery method (Ozempic uses pre-filled pens, Strive uses multi-dose vials), formulation additions (Strive may include glycine, B12, or B6), and cost (Ozempic costs $800 to $1,200 per month without insurance versus $90 to $200 per month for Strive)
Compounded Semaglutide Injection is $189/mo month-to-month (or $149/mo on the 6-month plan), while Compounded Tirzepatide Injection is $289/mo month-to-month, or from $249/mo on the 6-month plan
10.1002/tox.23388 166 NiJ.ChenK.ZhangJ.ZhangX
7 Lastly, investigational agents hold promise for new anti-obesity therapies that may sustain weight loss or minimize weight regain
