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10.1371/journal.pone.0062687 130 SepulvedaP

This phenomenon, which is known as the 'somatopause', has led to recombinant human GH being widely promoted and abused as an antiageing drug, despite lack of evidence of efficacy

Disagreements were resolved through discussion or by consultation with a fourth author (CS)

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Additionally, polyphenols can interfere with intracellular processes by impairing the activity of enzymes necessary for microbial survival, leading to reduced proliferation (344346)