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"Effects of Three Oral Nutritional Supplements on Human Hydration Indices"

Over the past several decades, its prevalence has risen at an alarming rate worldwide, reaching pandemic proportions and showing no signs of stabilization [1, 2]

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Similar to other peptide-bound GLP-1R structures 13, 16 , exendin-4 and oxyntomodulin adopted a continuous alpha helix, with their C-terminus bound within the ECD and their N-terminus bound deep within the TMD forming extensive interactions with residues within TM1, TM2, TM3 TM5, TM6, TM7 and ECL2 (Figures 1-2, Supplemental Figure 4)