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5 Whatever the method of brain GLP-1 receptor activation, the local brain effects are to increase satiety

However, as the effects do not persist over an entire 24 h period, its efficacy at lowering blood glucose levels and reducing body weight is lower than that of GLP-1 receptor agonists with a longer duration of action [3]

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This study was reported in accordance with the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) statement guidelines for cohort studies [27] which is listed in the supplementary information

The researchers concluded that residual differences between patient groups may partly explain the findings and that further studies are needed to determine whether the observed association reflects the medicines themselves or the underlying health of the people receiving them