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In PASC, the HMRD-amplified immune disruption could cause tissue damage and aggravate GI disorders such as loss of appetite, leaky gut with severe malnutrition

Nonetheless, the TMD conformation differed and, overall, the receptor was relatively stable, exhibiting less flexibility compared with GLP-1R bound to exendin-4 or oxyntomodulin (Supplementary Fig

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Peptides are stable only within specific pH ranges, and the formulation must be carefully buffered to maintain the correct pH throughout the products shelf life

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