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The company describes retatrutide as an investigational once-weekly triple-hormone receptor agonist that activates GIP, GLP-1, and glucagon receptors with a single molecule.[4] This development history is important because retatrutide was designed as a next-generation incretin therapy rather than as a simple modification of an existing GLP-1 agent

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Importantly, while traditional scaffolds primarily function as physical supports with limited versatility, and conventional treatments largely depend on such scaffolds, biomimetic microfiber scaffolds can load drugs, growth factors, or stem cells to achieve multifunctional regulation, such as antibacterial activity and angiogenesis promotion [198]

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