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Research suggests that GIP may actually reduce some of the gastrointestinal side effects associated with pure GLP-1 agonists, which explains why Retatrutide causes less nausea (28%) than semaglutide (44%) despite being more potent for weight loss

Advice Food supplements are not to be used as a substitute for a varied, balanced diet and healthy lifestyle

Studies indicate that emotional changes may be related to the medication's effects on brain regions involved in reward and motivation rather than direct mood alteration

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