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The diagram below is provided to show the interplay between cortisol and glutamate during acute stress

Wakefield AJ, Murch SH, Anthony A, Linnell J, Casson DM, Malik M, et al

302 Notably, microbial metabolites produced by commensal gut flora can limit pathogenic activities of microglia and astrocytes and suppress CNS inflammation in MS experimental models 303 and can contribute to the induction of specific LAMP1+TRAIL+ astrocytes that limit CNS inflammation by inducing T cell apoptosis

As scientific comprehension advances, the incorporation of sophisticated technologies such as artificial intelligence and machine learning is becoming progressively vital for predicting, evaluating, and mitigating these dangers (150)