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Although there is some confusion as to the precise movement of receptors at the plasma membrane, the specific location of MORs could have a potent influence on the association with effectors and downstream modulators

These effects are linked to its neuroprotective, anti-inflammatory, and vascular-promoting properties

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2.11 Separation and extraction of nuclear and cytoplasmic proteins In this experiment, nuclear and cytoplasmic fractionation was performed using the Nuclear and Cytoplasmic Protein Extraction Kit (Beyotime, P0027) following the manufacturers instructions