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Caroline Apovian, codirector of the Center for Weight Management and Wellness at Brigham and Womens Hospital in Boston, says that because compounded drugs are not reviewed for safety, quality, and effectiveness, there is potential for variation across compounded medications

*Eligible patients without diabetes but with a BMI of 30, or 27 with comorbidities, lost an average of 21% of their body weight (-48 lbs) in a 72-week clinical trial evaluating 15 mg of tirzepatide, when combined with a reduced-calorie diet and increased physical activity

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Past medical history, including diagnoses related to the Charlson Comorbidity Index (CCI), and the presence of gastroparesis prior to EGD were also extracted