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Specifically, a recent systematic review of 16 basic science studies showed cortisone may decrease tenocyte (tendon cell) viability and function while also weakening the structure of the tendon (Puzzitiello et al., Arthrosc Sport Med Rehabil , 2020)

These effects are real but fundamentally temporary: once you stop the compound, the neurochemical balance tends to revert

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The observed neuroprotective effects of A