A biomarker model consisting of six common metabolites (linoleic acid, prostaglandin D2, lysophosphatidylcholine (18:0), N-acetylhistamine, citric acid and indolelactic acid) AUC value of Receiver Operating Characteristic (ROC) curve was 0.978
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Results Small intestinal adaptations to increased food intake with cold stress require GLP-1R and GLP-2R signaling To determine the impact of GLP-1R, GLP-2R, or GIPR on gut surface area expansion with cold stress, we used double receptor knockout mice for Glp1r / Gipr / (DIRKO) and Glp1r / Glp2r / (GLPDRKO) to account for overlapping or compensatory roles in the intestinotrophic action of these gut hormones 15,35,46
