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it appears to recapitulate the intracellular signals that exercise generates, including AMPK activation, mitochondrial biogenesis, and GLUT4 upregulation, in tissues that can no longer experience them through movement

and disappear as your body adjusts to the medicine

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R., Juhl, C

Their study, reported in Frontiers in Behavioral Neuroscience, identified 30 clinical and 71 preclinical studies and data was presented by grouping: rodent studies on palatable food intake, drugs of abuse