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Autosomal dominant AD is associated with specific mutations in the amyloid precursor protein ( APP ), presenilin 1 ( PSEN1 ), or PSEN2 genes, while late-onset AD is significantly influenced by the presence of two copies of apolipoprotein 4 allele (Fetahu et al., 2019)

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doi: 10.3346/jkms.2011.26.7.927 112 SilveiraLGNoelSDSilveira-NetoAPAbreuAPBritoVNSantosMGet al

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