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in trial data, this effect appears to be offset by the concurrent GLP-1 and GIP activity, though the precise interplay in humans remains under investigation

Surgical-Level Results: Latest 2026 data shows an average weight loss of 28.7% to 30% over 68 weeksmatching the efficacy of some bariatric surgeries

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pre-op medication to reduce salivary & respiratory secretions used along in combination with neostigmine