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The cons are similar to those of Ozempic and Wegovy

For someone on the edge of prediabetes, that shift can meaningfully alter their long-term metabolic trajectory

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While Wegovy signals satiety through the glucagon-like peptide-1 receptor, prednisone simultaneously promotes cortisol-driven appetite stimulation, creating competing physiological signals

Long-acting GLP1 agonists should be discontinued for at least 1 week before the procedure (listed in Table 5)