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NHS England and the Department of Health and Social Care have issued guidance prioritising existing patients and those with greatest clinical need

Balestri, Martina, et al

allele frequency, 1.1%).[185] This allele results in normal production of an altered protein, and the authors hypothesized carriers have an increased sensitivity to environmental factors, which require DNA repair

As such, the data can be influenced by heightened awareness of side effects, such as through media attention or exposure to reports on social media

Many patients report breakthrough moments around week 3-4 when appetite suppression becomes pronounced, making meal planning and portion control feel effortless for the first time