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Pretreatment with IL-10-neutralizing antibodies blocked morroniside-induced -endorphin expression both in vivo and in vitro [74]

GI side effects that peaked in weeks 1 to 20 largely resolved by week 40, even as patients remained on full maintenance dosing [9]

This observation indicates that hormonal therapies aimed at contraception, alleviating menopausal symptoms, or treating estrogen receptor-positive breast cancer may interact with CIH, potentially modifying the responses of other tissues such as the lungs, cardiovascular system, brain, and kidneys in female OSAHS patients (61)

Hair loss Both menopause and rapid weight loss can trigger telogen effluvium, a temporary form of hair shedding

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