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Thus, although an important point to keep attention to, data so far does not indicate that cardiovascular complications are a major cause for concern at the moment (gastrointestinal problems being by far the larger problem experienced by people on GLP1R agonists )

If youre trying to understand how it fits into the current landscape of weight loss medications, and how it stacks up against GLP-1 options like semaglutide and tirzepatide, heres a clear-eyed look at what the evidence actually shows

May 4, 2009

That being said, this at minimum should match and possibly exceed the standard 2.4mg dose of semaglutide for weight loss

This phenomenon is thought to result from compensatory mechanisms, such as increased SGLT1 activity and upregulation of SGLT2 expression