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Long-term safety studies extending up to 12 months showed no adverse effects, which is rare for a compound with such potent biological activity

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BOC Sciences manufactures thousands of pharmaceutical impurities, degradations, metabolites of active pharmaceutical ingredients, and excipients in accordance with the guidelines and limits described in the international pharmacopeia monographs for many impurities to serve drug development

While fellow Capncollar family member NRF1 is the primary transcriptional regulator of proteasomal subunits under conditions that inhibit the proteasome or increase ER stress, NRF2 also regulates several proteasomal subunits, particularly during oxidative stress

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