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The most important transcription factor in the regulation of antioxidant enzymes is NRF-2 [66]

However, more recent studies assessing the role of ferrous iron in the pathophysiology first in vitro [74, 75] and then in vivo [76, 77] provided evidence that after a toxic dose of APAP ferrous iron derived from lysosomes is taken up into mitochondria through a Ca 2+ uniporter and facilitates the MPTP opening and cell death

The tripeptide GLY-HIS-LYS influence on behavior of rats in the test open field

Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood

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