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PfGrx shares 39% sequence identity with human Grx1, including a CPYC motif and a semiconserved GGC motif, and is well characterized in vitro and in roGFP2 assays in yeast 14,26,30,35

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The CAROLINA study is the only prospective cardiovascular outcomes study to directly compare major adverse cardiovascular events of a DPP-4 inhibitor (linagliptin) with a SU (glimepiride)

doi: 10.1186/ar3685 39 van KuijkAWVergunstCEGerlagDMBresnihanBGomez-ReinoJJRouzierRet al

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