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The combination of three genes, CDO1 (cysteine dioxygenase type 1), HOXA9 (homeobox A9), and TAC1 (tachykinin, precursor 1) has shown great promise in both the early diagnosis and staging of NSCLC (Wrangle et al., 2014)

J Clin Invest 124:10371051 Thomas C, Gioiello A, Noriega L et al (2009) TGR5-mediated bile acid sensing controls glucose homeostasis