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Safety: The most common side effects are mild gastrointestinal symptoms, such as nausea or diarrhea, which typically improve with time
Lawsuits were filed alleging that the manufacturer knew about the risks from early trial data but pushed for FDA approval anyway
Studies have shown that slowing down gut transit decreases fecal sulfate, meaning more sulfate remains available in the gut for bacterial metabolism (and, thus, hydrogen sulfide gas production!)
This dose should be maintained for at least four weeks to assess tolerance and initial therapeutic response before considering further dose escalation
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