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(2003) demonstrated that Epithalon increased telomerase activity in human somatic cells by 2.4-fold A 15-year follow-up study of elderly patients showed that those receiving peptide bioregulators (including Epithalon) had a 28% reduction in mortality compared to controls Animal studies have shown increased lifespan of up to 13.3% in organisms treated with Epithalon, as reported in research published through the National Institute on Aging Studies on retinal pigment epithelium cells showed Epithalons ability to reactivate telomerase in senescent cells While more large-scale human clinical trials are needed, the existing body of research is substantial and encouraging