Current evidence suggests: Positive Safety Indicators: No toxicity observed in animal studies at therapeutic doses Selective mechanism reduces off-target effects No evidence of organ damage or dysfunction Reversible effects upon discontinuation Areas Requiring Further Study: Long-term effects on NNMT function Impact on methylation processes over extended periods Potential effects on fertility and reproduction Interactions with aging processes Regulatory Status and Quality Considerations 5-Amino-1MQ is not FDA-approved for any medical use and exists as a research compound
17.Barlow, P
Clinical studies demonstrate strong correlations between OS markers and vascular complications including diabetic kidney disease (Forbes and Thorburn, 2018
Oxidative Med Cell Longev 2016:18 Garcia-Bello JA, Gmez-Daz RA, Contreras-Rodrguez A, Talavera JO, Mondragn-Gonzlez R, Sanchez-Barbosa L, Diaz-Flores M, Valladares-Salgado A, Gallardo JM, Aguilar-Kitsu A, Lagunas-Munoz J, Wacher NH (2014) Carotid intima media thickness, oxidative stress, and inflammation in children with chronic kidney disease
So I would imagine also there would be so what's this