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There is little research around the safety of milk thistle for pregnant or breastfeeding women so its best to avoid it under these circumstances

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Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer: 10-year results of the randomized controlled EORTC 10981-22023 AMAROS trial

Key liver function markers, including ALT, TBIL, and ALB, showed notable enhancements, with ALT levels decreasing from 348.96 U/L to 31.11 U/L in the observation group, compared to 347.90 U/L to 56.90 U/L in the control group

Sometimes its all of the above