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Ion Signaling Phosphorylation indirectly controls TJ permeability by acting on associated proteins

Furthermore, mutations in genes involved in IL-17 production and TJ protein expression are associated with the development of IBD (Sartor 1997)

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The performance of the mannitol excretion test in other disease conditions and treatments will need to be evaluated and compared against the multitude of studies using a combined assessment of lactulose and mannitol excretion (13)