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Animals and treatments Female Kunming strain mice at 23 mo old (outbreed albino mice originated from the ICR strain) were obtained from the Experimental Animal Center of the Fourth Military Medical University (Xian, China) and housed in a temperature-controlled animal facility, kept on a cycle of 12 h light and 12 h dark with free access to food and water

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Ken Geraldi, Ms

B12 supports normal energy production and pairs well with nutrition coaching and exercise

FIGURE 2 NAD + can act as a cosubstrate for sirtuins (SIRT) (Verdin, 2015), class III histone deacetylase enzymes whose activity is dependent on NAD + levels (Tang, 2016