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You should not use semaglutide if you: Semaglutide may not be safe if you: Are pregnant, planning pregnancy, or breastfeeding Have personal or family history of medullary thyroid cancer Have Multiple Endocrine Neoplasia Syndrome type 2 (MEN2) Have a history of pancreatitis Have experienced serious allergic reactions to semaglutide Have severe kidney or liver disease A licensed provider will review your medical history before prescribing