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The molecule makes three changes to the native hormone fragment: a lactam bridge between the aspartate side-chain carboxyl at position 5 and the lysine side-chain amine at position 10, inversion to D-phenylalanine at position 7, and substitution of norleucine for the oxidation-prone methionine at position 4
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10 On the day of the procedure, the anesthesia provider should complete a thorough interview to assess the patient for GI symptoms, including nausea, vomiting, retching, diarrhea, abdominal bloating, or abdominal pain
Evidence on other potential uses, such as weight control or sexual dysfunction, remains inconclusive
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