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Scarr, E., Pavey, G., Sundram, S., MacKinnon, A

Summarizing we provide a detailed characterization of the interaction of p53 with FOXO4 and FOXO4-DRI which is the basis for development of p53 inhibitors to treat diseases linked to cellular senescence such as cancers

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( G ) Schematic showing hepatic GSH depletion by Chac1 overexpression protects from MASLD through selective protein oxidation and transcriptional regulation

Esterase-activated theranostic prodrug for dual organelles-targeted imaging and synergetic chemo-photodynamic cancer therapy