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(MD, DO, DPM, DDS, PA, NP, CRNA, CNM, & DVM)

Inhibition of KEAP1 by RTA 408 disinhibits the antioxidant transcription factor nrf2 and has neuroprotective and seizure reducing effects in the kainic model of TLE (Shekh-Ahmad et al., 2018)

Reality: Freezing destroys the medication's structure and renders it ineffective, regardless of how well it appears to be preserved

These measures may include adherence to a 24-hour liquid-only diet before the procedure, utilization of point-of-care gastric ultrasound to assess gastric contents when expertise is available, modification of anesthetic technique to incorporate aspiration-prevention strategies, or temporary postponement of elective procedures when risk factors are expected to improve with time

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