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Intriguingly, OWL-833 has a similar signalling and regulatory profile to that of TT-OAD2, where neither agonist promoted -arrestin recruitment or internalisation and both were also very poor agonists for pERK1/2 and calcium mobilisation

doi: 10.1007/s40618-014-0136-z 18 LanzollaGVannucchiGIonniICampiISikahalyFLazzaroniEet al