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In compounded form as a number of Sonoma County firefighters and their advocates testified during the meetings several comment periods it has shown promise in lowering levels of toxins often found in high concentrations in the bodies of some firefighters

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thus, the optimal timing of such therapies is essential for enhancing the response to treatment

Further studies showed that berberine enhanced the activities of glutathione peroxidase, glutathione, superoxide dismutase, and catalase, further reducing the activity of acetylcholinesterase and caspase-3, protein carbonyl, and DNA fragmentation in the hippocampus (Sadraie et al., 2019)