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More recent work by Jerry Turner and others [29, 41] has provided substantial data supporting the presence of two distinct paracellular pathways: the pore pathways that transports ions and small uncharged molecules, and the leak pathway that transports larger molecules regardless of charge

This mechanistic profile is why it appears in research spanning both areas

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Methylated B12 is studied for its role in methylation-dependent biological processes, including biochemical pathways related to homocysteine metabolism, nervous-system function, red blood cell biology, and cellular energy regulation