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A woman with a BMI of 36 and a history of repeated weight regain completes a medical evaluation

This is because tirzepatide is not just a GLP-1 receptor agonist but also a GIP receptor agonist, making it more potent in some respects and potentially more likely to cause gastrointestinal side effects in the early weeks

From $129 Insurance Eligibility Check Comprehensive insurance eligibility verification for GLP-1 coverage

The interaction does not prevent using these medications together, but it may require levothyroxine dose adjustments as T4 levels may run higher than expected

They were also more likely to achieve clinically meaningful milestones like losing 5% or 10% of their starting weight