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Tirzepatide, like other agents in this class, requires monitoring for dehydration and potential effects on diabetic retinopathy, particularly during rapid improvement in glucose control

Xerostomia of the oral cavity is mostly induced by reduced secretion of saliva

doi: 10.1016/0006-2952(81)90576-1

Antibody titer was determined as the highest dilution factor for each mouse with a higher OD value than background, where the background is the mean absorbance of mice given NaCl plus 5x the standard error of the mean of the same observations

Quantification of hepatic GSH and MDA Hepatic content of GSH and glutathione disulfide (GSSG) was measured using the GSSG/GSH Quantification kit (Dojindo, Kumamoto, Japan) in accordance with the manufacturers instructions