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Abstract Enteroendocrine cells lining the gut epithelium constitute the largest endocrine organ in the body and secrete over 20 different hormones in response to cues from ingested foods and changes in nutritional status

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However, a University of Pennsylvania study showed 53.6% of GLP-1 users stop within one year, while 75% of users quit completely within two years, a Prime Therapeutics/Magellan Rx study concluded

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