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Summary Delta-Sleep-Inducing Peptide (DSIP) stands out as a groundbreaking neuropeptide, known for its role in sleep regulation

With aging, the number of Leydig cells per testis remains unchanged, but these cells may exhibit a reduced capacity for testosterone synthesis, resulting in an age-related decline of serum testosterone levels [8, 9]

In addition, we did not conduct metabolite analysis in tissues, especially in target organs, owing to the small sample size

Modern research increasingly describes a gutmetabolic axis, a complex network connecting intestinal health with systemic metabolic regulation