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Studies show GLP-1 use in post-cholecystectomy patients is generally safe when monitored, but reports of diarrhea, bile acid malabsorption, and pancreatitis occur at slightly higher rates

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This metabolic shift occurs due to the peptides action on the nicotinamide methylation pathway , which increases intracellular NAD+ availability, facilitating greater oxidative metabolism

Given the limitations in accurately quantifying body composition using more accessible body compositional measurement tools (e.g., bioelectrical impedance), physical function should also be monitored