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9 Nrf2 is usually locked in the cytoplasm, but activation by DMF/MMF allows it to translocate to the nucleus where it activates a pathway of genes involved in antioxidant responses, detoxification, and the activity of cytoprotective anti-inflammatory factors

Bjrklund, G., Tinkov, A

These slow digestion even more and can amplify nausea or reflux in people on GLP-1 therapy. Carbonated drinks and alcohol can make bloating worse, Vedala says

Because decaf coffee is low in calories and rich in antioxidants called polyphenols, it can support body composition and digestion while replacing higher-calorie drinks

Moreover, the literature points out that berberine has inhibitory effects on four key enzymes related to the pathogenesis of Alzheimer s disease: monoamine oxidase B (MAO-B), acetylcholinesterase, monoamine oxidase A (MAO-A), and butyrylcholinesterase (Yuan et al., 2019)