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For many research protocols, particularly those involving long-term observations or where ease of administration is a significant factor, an oral compound is often the first choice

It also acts as an intermediate in the pathway for valine, threonine, methionine, thymine, isoleucine, cholesterol and odd-chain fatty acids

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Bone and osteoarthritis models some animal studies have looked at effects on bone density and joint tissue, though this research is still at an early stage