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10.1002/path.2697 54 Gmez-SierraT.Eugenio-PrezD.Snchez-ChinchillasA.Pedraza-ChaverriJ

Consequently, intracellular GSH levels were elevated (Figs

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If naloxone is prescribed, educate patients and caregivers on how to treat with naloxone [see WARNINGS, Addiction, Abuse, and Misuse, Risks from Concomitant Use with Benzodiazepines or Other CNS Depressants;PRECAUTIONS, Information for Patients and/or Caregivers, Overdosage]

Ferroptosis, introduced by Dixon in 2012, is an iron-dependent form of programmed cell death (PCD) that primarily impacts cellular organelle structures, particularly mitochondrial architecture, and is marked by the buildup of lipid peroxides [51,52]