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[1] Note the comparator carefully: it was liraglutide, not tirzepatide

Li, G.D

It highlights the ability of peripheral liraglutide to cross the BBB and specifically target hypothalamic ARC cells, eliciting significant appetite suppression and subsequent weight loss

AOD9604 appears to stimulate proteoglycan and collagen synthesis in chondrocytes through growth factor signaling pathways distinct from its lipolytic mechanism, supporting cartilage matrix repair in joint models

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