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Moreover, the FINEARTS-HF trial showed that compared with placebo, finerenone resulted in a significant reduction in worsening heart failure events and cardiovascular death in patients with left ventricular ejection fraction 40%.88 These findings extend the utility of finerenone beyond CKD management, reinforcing its broad applicability across cardiometabolic and heart failure syndromes

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For each tested enzyme of the carnitine biosynthetic pathway from N

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[PubMed: 38992799] 56