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This antioxidant function protects cells from oxidative damage, supporting overall health

10.1007/BF02172145 45

Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1

The non-significant beneficial effect of GSH supplementation on oxidative stress and antioxidant capacities might be due to inadequate selenium status in our cirrhosis patients

The predicted 16 PARylation sites of RSMC were labeled (K53, K106, K107, R30, R31, R33, R35, K52, S65, E87, E89, S98, K103, R104, D113, E115, in black)