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However, their ability to dramatically improve metabolic health markers (insulin sensitivity, visceral fat, inflammation) addresses major drivers of biological aging

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Additionally, preclinical research suggests GLP-1 receptors may be present in various tissues beyond the pancreas and brain, including synovial tissue and chondrocytes

In this context, our data indicates that a metabolic shift from oxidative to glycolytic metabolism represents an escape mechanism for breast cancer cells chronically-treated with a mitochondrial stressor like Doxycycline, as mitochondrial dys-function leads to a stronger dependence on glucose