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Show details Figure 17, Pooled mean between-group difference in hemoglobin A1c comparing a co...Figure 17, Pooled mean between-group difference in hemoglobin A1c comparing a combination of metformin plus a DPP-4 inhibitor with a combination of metformin plus a GLP-1 receptor agonist - Diabetes Medications for Adults With Type 2 Diabetes: An Update Your browsing activity is empty

Unlike nausea or appetite changeswhich are well-documented GLP-1 effectsbody aches appear to occur in a smaller subset of users

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doi: 10.14814/phy2.13998

[1] [13] When B12 levels are borderline or clinical suspicion remains high despite normal B12, additional tests include: Holotranscobalamin (active B12) , which may be more sensitive in early or borderline deficiency Methylmalonic acid (MMA) and homocysteine levels, which become elevated in functional B12 deficiency (note that MMA is also elevated in renal impairment, and homocysteine rises in folate and B6 deficiency) Full blood count to identify macrocytic anaemia (elevated mean cell volume) Blood film examination may show hypersegmented neutrophils and megaloblastic changes Serum folate should be checked concurrently, as deficiencies often coexist Investigating the underlying cause is essential for appropriate management