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Melatonin is known to have a variety of biological functions, including circadian rhythm regulation, anti-inflammatory, free radical scavenging, edema reduction, suppression of the hypothalamic-pituitary endocrine axis, suppression of cancer, stimulation of mitochondrial biogenesis, immunomodulation, blood pressure regulation and the epigenetic regulation, and has therapeutic effects on a variety of secondary injuries after SCI ( The intestinal microbiota can act on the CNS through the microbial gut-brain axis

Trimetazidine is a selective inhibitor of 3-ketoacyl-CoA thiolase, a key enzyme in fatty acid oxidation [121]

Ciccarelli et al., 2012

In addition, Cox2, the marker of lipid peroxidation during ferroptosis, was significantly reduced after DMF treatment

Upon receiving a warm package, first check the packaging for any temperature monitoring devices, such as temperature indicators or data loggers, which some specialty pharmacies include with temperature-sensitive biologics